YLR378C

Description : Conserved ER protein translocation channel; essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms channel for SRP-dependent protein import; with Sec63 complex allows SRP-independent protein import into ER; involved in posttranslational soluble protein import into the ER, ERAD of soluble substrates, and misfolded soluble protein export from the ER [Source:SGD;Acc:S000004370]

Gene families : OG_03_0001066 (OF) Phylogenetic Tree(s): OG0001066_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YLR378C
Cluster	HCCA: Cluster_39

Target	Alias	Description	ECC score	Gene Family Method
AFR97269	No alias	protein transporter SEC61 subunit alpha;SecY...	0.05	OF
AOA65539	No alias	Translocon Sec61/SecY, plug domain	0.13	OF
AOA66872	No alias	SecY/SEC61-alpha family	0.04	OF
CAG79843	No alias	Translocon Sec61/SecY, plug domain	0.1	OF
CAK47873	No alias	Plug domain of Sec61p	0.11	OF
CBF79973	No alias	hypothetical protein similar to Sec61	0.13	OF
EAA29599	No alias	Translocon Sec61/SecY, plug domain	0.08	OF
EAL91785	No alias	protein transport protein Sec61 alpha subunit, putative	0.1	OF
EAU80981	No alias	protein transporter	0.07	OF
EDN91224	No alias	SecY/SEC61-alpha family	0.06	OF
EGR49352	No alias	SecY/SEC61-alpha family	0.12	OF
EJF57023	No alias	Plug domain of Sec61p	0.05	OF
ESU15530	No alias	transporter SEC61 subunit alpha	0.06	OF
KHC79315	No alias	protein transporter SEC61 subunit alpha;SecY...	0.13	OF
KHC83326	No alias	protein transporter SEC61 subunit alpha;Plug domain of...	0.04	OF
MGG_04856T0	No alias	Protein transporter SEC61 subunit alpha...	0.05	OF
SPBC354.02c.1	No alias	translocon alpha subunit Sec61 [Source:PomBase;Acc:SPBC354.02c]	0.05	OF

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0015031	protein transport	IEA	Interproscan
BP	GO:0015833	peptide transport	None	Extended
CC	GO:0016020	membrane	IEA	Interproscan
BP	GO:0033036	macromolecule localization	None	Extended
BP	GO:0042886	amide transport	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR019561	Translocon_Sec61/SecY_plug_dom	41	75
IPR002208	SecY/SEC61-alpha	76	458

External Links

No external refs found!

YLR378C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation