Description : Conserved ER protein translocation channel; essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms channel for SRP-dependent protein import; with Sec63 complex allows SRP-independent protein import into ER; involved in posttranslational soluble protein import into the ER, ERAD of soluble substrates, and misfolded soluble protein export from the ER [Source:SGD;Acc:S000004370]
Gene families : OG_03_0001066 (OF) Phylogenetic Tree(s): OG0001066_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLR378C | |
Cluster | HCCA: Cluster_39 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR97269 | No alias | protein transporter SEC61 subunit alpha;SecY... | 0.05 | OF | |
AOA65539 | No alias | Translocon Sec61/SecY, plug domain | 0.13 | OF | |
AOA66872 | No alias | SecY/SEC61-alpha family | 0.04 | OF | |
CAG79843 | No alias | Translocon Sec61/SecY, plug domain | 0.1 | OF | |
CAK47873 | No alias | Plug domain of Sec61p | 0.11 | OF | |
CBF79973 | No alias | hypothetical protein similar to Sec61 | 0.13 | OF | |
EAA29599 | No alias | Translocon Sec61/SecY, plug domain | 0.08 | OF | |
EAL91785 | No alias | protein transport protein Sec61 alpha subunit, putative | 0.1 | OF | |
EAU80981 | No alias | protein transporter | 0.07 | OF | |
EDN91224 | No alias | SecY/SEC61-alpha family | 0.06 | OF | |
EGR49352 | No alias | SecY/SEC61-alpha family | 0.12 | OF | |
EJF57023 | No alias | Plug domain of Sec61p | 0.05 | OF | |
ESU15530 | No alias | transporter SEC61 subunit alpha | 0.06 | OF | |
KHC79315 | No alias | protein transporter SEC61 subunit alpha;SecY... | 0.13 | OF | |
KHC83326 | No alias | protein transporter SEC61 subunit alpha;Plug domain of... | 0.04 | OF | |
MGG_04856T0 | No alias | Protein transporter SEC61 subunit alpha... | 0.05 | OF | |
SPBC354.02c.1 | No alias | translocon alpha subunit Sec61 [Source:PomBase;Acc:SPBC354.02c] | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0015031 | protein transport | IEA | Interproscan |
CC | GO:0016020 | membrane | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |