YLR371W

Description : Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEF; Rom2p localization to the bud surface is dependent on Ack1p; ROM2 has a paralog, ROM1, that arose from the whole genome duplication [Source:SGD;Acc:S000004363]

Gene families : OG_03_0001137 (OF) Phylogenetic Tree(s): OG0001137_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YLR371W
Cluster	HCCA: Cluster_56

Target	Alias	Description	ECC score	Gene Family Method
AFR96851	No alias	rho guanyl-nucleotide exchange factor;RhoGEF...	0.09	OF
AOA68611	No alias	Pleckstrin homology domain 5	0.09	OF
CAG83379	No alias	Pleckstrin homology domain 5	0.04	OF
CAK39428	No alias	CNH domain	0.12	OF
CBF76930	No alias	conserved hypothetical protein similar to Rho guanine...	0.11	OF
EAA36572	No alias	Pleckstrin homology domain 5	0.09	OF
EAL91744	No alias	Rho guanyl nucleotide exchange factor (Rom2), putative	0.13	OF
EAU90407	No alias	signal transducer	0.02	OF
EDO00705	No alias	Citron homology (CNH) domain	0.13	OF
EED81862	No alias	Dbl homology (DH) domain	0.04	OF
EFI27376	No alias	RhoGEF Rgf2	0.07	OF
EGR46691	No alias	Citron homology (CNH) domain	0.17	OF
EJF59044	No alias	RhoGEF domain	0.05	OF
ESU14753	No alias	Citron homology (CNH) domain	0.15	OF
KHC81384	No alias	hypothetical protein;"Domain found in Dishevelled,...	0.09	OF
MGG_03064T0	No alias	Rho1 guanine nucleotide exchange factor 1...	0.05	OF
POV95364	No alias	Dbl homology (DH) domain;Citron homology (CNH)...	0.03	OF
SPAC1006.06.1	No alias	RhoGEF Rgf2 [Source:PomBase;Acc:SPAC1006.06]	0.12	OF
SPCC645.07.1	No alias	RhoGEF for Rho1, Rgf1 [Source:PomBase;Acc:SPCC645.07]	0.17	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005085	guanyl-nucleotide exchange factor activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
BP	GO:0007165	signal transduction	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0019899	enzyme binding	None	Extended
BP	GO:0035556	intracellular signal transduction	IEA	Interproscan
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
MF	GO:0051020	GTPase binding	None	Extended
BP	GO:0065007	biological regulation	None	Extended
MF	GO:0098772	molecular function regulator	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR041675	PH_5	881	1011
IPR000591	DEP_dom	432	501
IPR000219	DH-domain	664	844
IPR001180	CNH_dom	1041	1332

External Links

No external refs found!

YLR371W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation