YLR127C

Description : Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the catalytic core of the APC/C; has similarity to cullin Cdc53p [Source:SGD;Acc:S000004117]

Gene families : OG_03_0003670 (OF) Phylogenetic Tree(s): OG0003670_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YLR127C
Cluster	HCCA: Cluster_3

Target	Alias	Description	ECC score	Gene Family Method
CAL00375	No alias	Anaphase promoting complex (APC) subunit 2	0.03	OF
EAA35080	No alias	Anaphase-promoting complex subunit 2, C-terminal	0.02	OF
ESU06317	No alias	Cullin, N-terminal	0.02	OF
SPBP23A10.04.1	No alias	anaphase-promoting complex cullin family subunit Apc2...	0.05	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	Interproscan
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019899	enzyme binding	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
MF	GO:0031625	ubiquitin protein ligase binding	IEA	Interproscan
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
MF	GO:0044389	ubiquitin-like protein ligase binding	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001373	Cullin_N	575	734
IPR014786	APC_su2_C	784	844

External Links

No external refs found!

YLR127C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation