Description : Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the catalytic core of the APC/C; has similarity to cullin Cdc53p [Source:SGD;Acc:S000004117]

Gene families : OG_03_0003670 (OF) Phylogenetic Tree(s): OG0003670_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YLR127C
Cluster HCCA: Cluster_3

Target Alias Description ECC score Gene Family Method Actions
CAL00375 No alias Anaphase promoting complex (APC) subunit 2 0.03 OF
EAA35080 No alias Anaphase-promoting complex subunit 2, C-terminal 0.02 OF
ESU06317 No alias Cullin, N-terminal 0.02 OF
SPBP23A10.04.1 No alias anaphase-promoting complex cullin family subunit Apc2... 0.05 OF

Type GO Term Name Evidence Source
BP GO:0006511 ubiquitin-dependent protein catabolic process IEA Interproscan
MF GO:0031625 ubiquitin protein ligase binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001373 Cullin_N 575 734
IPR014786 APC_su2_C 784 844
No external refs found!