YLL002W


Description : Histone acetyltransferase; critical for cell survival in presence of DNA damage during S phase, required for recovery after DSB repair; acetylates H3K56, H3K9; H3K56 acetylation activity required for expression homeostasis, buffering of mRNA synthesis rate against changes in gene dosage during S phase; involved in non-homologous end joining and regulation of Ty1 transposition; prevents hyper-amplification of rDNA; interacts physically with Vps75p [Source:SGD;Acc:S000003925]


Gene families : OG_03_0001234 (OF) Phylogenetic Tree(s): OG0001234_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLL002W
Cluster HCCA: Cluster_53

Target Alias Description ECC score Gene Family Method Actions
AOA68698 No alias Histone acetyltransferase Rtt109/CBP 0.02 OF
MGG_05969T0 No alias Putative uncharacterized protein... 0.02 OF
SPBC342.06c.1 No alias RTT109 family histone lysine acetyltransferase... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0004402 histone acetyltransferase activity IEA Interproscan
BP GO:0006355 regulation of transcription, DNA-templated IEA Interproscan
BP GO:0016573 histone acetylation IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR013178 Histone_AcTrfase_Rtt109/CBP 3 411
No external refs found!