YKR063C

Description : Endonuclease involved in pre-rRNA processing at both ends of ITS2; functions with Grc3p in a conserved mechanism to modulate rRNA processing and ribosome biogenesis; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S cell cycle transition; human ortholog is Las1L; mutants require the SSD1-v allele for viability [Source:SGD;Acc:S000001771]

Gene families : OG_03_0001602 (OF) Phylogenetic Tree(s): OG0001602_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YKR063C
Cluster	HCCA: Cluster_23

Target	Alias	Description	ECC score	Gene Family Method	Actions
AOA65852	No alias	Las1	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004519	endonuclease activity	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006364	rRNA processing	IEA	Interproscan
BP	GO:0006396	RNA processing	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0016072	rRNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0034470	ncRNA processing	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
CC	GO:0090730	Las1 complex	IEA	Interproscan
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1902555	endoribonuclease complex	None	Extended
CC	GO:1902911	protein kinase complex	None	Extended
CC	GO:1905348	endonuclease complex	None	Extended
CC	GO:1905354	exoribonuclease complex	None	Extended
CC	GO:1990234	transferase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR007174	Las1	7	161

External Links

No external refs found!

YKR063C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation