YAL012W

Description : Cystathionine gamma-lyase; catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000010]

Gene families : OG_03_0001702 (OF) Phylogenetic Tree(s): OG0001702_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YAL012W
Cluster	HCCA: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method
CBF84873	No alias	Cystathionine gamma-lyase	0.02	OF
EAA34571	No alias	Cys/Met metabolism, pyridoxal phosphate-dependent enzyme	0.05	OF
EAL85203	No alias	cystathionine gamma-lyase	0.02	OF
EED79739	No alias	Cys/Met metabolism, pyridoxal phosphate-dependent enzyme	0.03	OF
EED84033	No alias	Cys/Met metabolism, pyridoxal phosphate-dependent enzyme	0.05	OF
EGR47606	No alias	Cys/Met metabolism, pyridoxal phosphate-dependent enzyme	0.04	OF
EJF56730	No alias	Cys/Met metabolism PLP-dependent enzyme	0.04	OF

Type	GO Term	Name	Evidence	Source
BP	GO:0000096	sulfur amino acid metabolic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006534	cysteine metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009069	serine family amino acid metabolic process	None	Extended
BP	GO:0009092	homoserine metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0019346	transsulfuration	IEA	Interproscan
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0019842	vitamin binding	None	Extended
MF	GO:0030170	pyridoxal phosphate binding	IEA	Interproscan
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
BP	GO:0050667	homocysteine metabolic process	None	Extended
MF	GO:0070279	vitamin B6 binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR000277	Cys/Met-Metab_PyrdxlP-dep_enz	10	390

External Links

No external refs found!

YAL012W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation