Description : Alpha subunit of translation initiation factor eIF2B; guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; positive regulator of GCN4 expression; assembles into filaments with Gcd2p, Gcd6p, Gcd7p, and Sui2p as cells approach stationary phase and under cytosolic acidification and starvation conditions; human homolog EIF2B1 can complement yeast null mutant [Source:SGD;Acc:S000001734]

Gene families : OG_03_0002711 (OF) Phylogenetic Tree(s): OG0002711_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YKR026C
Cluster HCCA: Cluster_55

Target Alias Description ECC score Gene Family Method Actions
AOA70387 No alias Initiation factor 2B-related 0.06 OF
CAG82284 No alias Initiation factor 2B-related 0.02 OF
CAK43267 No alias Initiation factor 2 subunit family 0.02 OF
ESU11636 No alias Initiation factor 2B-related 0.04 OF
KHC71808 No alias translation initiation factor eIF-2B subunit... 0.05 OF

Type GO Term Name Evidence Source
BP GO:0044237 cellular metabolic process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000649 IF-2B-related 17 292
No external refs found!