YKR026C

Description : Alpha subunit of translation initiation factor eIF2B; guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; positive regulator of GCN4 expression; assembles into filaments with Gcd2p, Gcd6p, Gcd7p, and Sui2p as cells approach stationary phase and under cytosolic acidification and starvation conditions; human homolog EIF2B1 can complement yeast null mutant [Source:SGD;Acc:S000001734]

Gene families : OG_03_0002711 (OF) Phylogenetic Tree(s): OG0002711_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YKR026C
Cluster	HCCA: Cluster_55

Target	Alias	Description	ECC score	Gene Family Method
AOA70387	No alias	Initiation factor 2B-related	0.06	OF
CAG82284	No alias	Initiation factor 2B-related	0.02	OF
CAK43267	No alias	Initiation factor 2 subunit family	0.02	OF
ESU11636	No alias	Initiation factor 2B-related	0.04	OF
KHC71808	No alias	translation initiation factor eIF-2B subunit...	0.05	OF

Type	GO Term	Name	Evidence	Source
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0044237	cellular metabolic process	IEA	Interproscan

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR000649	IF-2B-related	17	292

External Links

No external refs found!

YKR026C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation