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  5. YKL139W

YKL139W


Description : Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]


Gene families : OG_03_0000159 (OF) Phylogenetic Tree(s): OG0000159_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YKL139W
Cluster HCCA: Cluster_23

Target Alias Description ECC score Gene Family Method Actions
AFR97868 No alias CMGC/CDK/CDC2 protein kinase;Protein kinase domain 0.02 OF
AOA67635 No alias Protein kinase domain 0.04 OF
AOA69042 No alias Protein kinase domain 0.03 OF
CAG81370 No alias Protein kinase domain 0.07 OF
CAL00814 No alias Protein kinase domain 0.02 OF
EAA26759 No alias Protein kinase domain 0.02 OF
EAA30881 No alias Protein kinase domain 0.02 OF
EAL85989 No alias protein kinase, putative 0.05 OF
EED84367 No alias Protein kinase domain 0.03 OF
EFI27713 No alias CMGC/CDK/CRK7 protein kinase 0.02 OF
EGR53109 No alias Protein kinase domain 0.04 OF
EJF61238 No alias Protein kinase domain 0.04 OF
ESU12937 No alias Protein kinase domain 0.04 OF
MGG_07291T0 No alias CMGC/CDK/CRK7 protein kinase [Source:UniProtKB/TrEMBL;Acc:G4MUX8] 0.05 OF
SPBC32H8.10.1 No alias P-TEFb-associated cyclin-dependent protein kinase Cdk9... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0004672 protein kinase activity IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0006468 protein phosphorylation IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR000719 Prot_kinase_dom 185 469
No external refs found!