YJR139C

Description : Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase); dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions [Source:SGD;Acc:S000003900]

Gene families : OG_03_0001857 (OF) Phylogenetic Tree(s): OG0001857_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	HRR: YJR139C
Cluster	HCCA: Cluster_67

Target	Alias	Description	ECC score	Gene Family Method
CAG80456	No alias	Homoserine dehydrogenase, catalytic	0.02	OF
CAK37707	No alias	Homoserine dehydrogenase, NAD binding domain	0.03	OF
KHC83043	No alias	homoserine dehydrogenase;"Homoserine dehydrogenase, NAD...	0.03	OF
SPBC776.03.1	No alias	homoserine dehydrogenase (predicted)...	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	IEA	Interproscan
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	IEA	Interproscan
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050661	NADP binding	IEA	Interproscan
MF	GO:0050662	coenzyme binding	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001342	HDH_cat	151	353
IPR005106	Asp/hSer_DH_NAD-bd	12	142

External Links

No external refs found!

YJR139C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation