Description : Essential ATP-binding protein required for DNA replication; component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p; relocalizes from nucleus to cytoplasm upon DNA replication stress; degraded in response to plasma membrane stress [Source:SGD;Acc:S000003730]

Gene families : OG_03_0002659 (OF) Phylogenetic Tree(s): OG0002659_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YJL194W
Cluster HCCA: Cluster_36

Target Alias Description ECC score Gene Family Method Actions
AOA69292 No alias ATPase, AAA-type, core 0.01 OF
CAG81590 No alias AAA lid domain 0.02 OF
CAK41488 No alias CDC6, C terminal winged helix domain 0.02 OF
CBF81423 No alias cell division control protein Cdc6, putative 0.02 OF
EAU91155 No alias Cdc6B protein 0.03 OF
EDO02040 No alias Cdc6, C-terminal 0.03 OF
SPBC14C8.07c.1 No alias MCM loader [Source:PomBase;Acc:SPBC14C8.07c] 0.04 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR003593 AAA+_ATPase 102 263
IPR015163 Cdc6_C 418 485
No external refs found!