Description : Essential ATP-binding protein required for DNA replication; component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p; relocalizes from nucleus to cytoplasm upon DNA replication stress; degraded in response to plasma membrane stress [Source:SGD;Acc:S000003730]
Sample enrichment: gal, 4h + hu 200 mm,WT (SPM: 0.42, entropy: 3.25, tau: 0.76)