Description : Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein complex involved in DNA replication, repair, recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003709]
Gene families : OG_03_0051432 (OF) Phylogenetic Tree(s): No tree available for this family
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YJL173C | |
Cluster | HCCA: Cluster_15 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003677 | DNA binding | IEA | Interproscan |
CC | GO:0005634 | nucleus | IEA | Interproscan |
BP | GO:0006260 | DNA replication | IEA | Interproscan |
BP | GO:0006281 | DNA repair | IEA | Interproscan |
BP | GO:0006310 | DNA recombination | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR013970 | Rfa2 | 1 | 122 |
No external refs found! |