YJL125C

Description : Subunit of tRNA (1-methyladenosine) methyltransferase; required, along with Gcd10p, for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression [Source:SGD;Acc:S000003661]

Gene families : OG_03_0001473 (OF) Phylogenetic Tree(s): OG0001473_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YJL125C
Cluster	HCCA: Cluster_16

Target	Alias	Description	ECC score	Gene Family Method
AFR98917	No alias	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit...	0.14	OF
AOA69249	No alias	tRNA (1-methyladenosine) methyltransferase catalytic...	0.14	OF
CAG78574	No alias	tRNA (1-methyladenosine) methyltransferase catalytic...	0.13	OF
CAL00262	No alias	tRNA methyltransferase complex GCD14 subunit	0.02	OF
CBF77998	No alias	tRNA methyltransferase subunit GCD14, putative	0.09	OF
EAL91639	No alias	tRNA methyltransferase subunit GCD14, putative	0.11	OF
EDN96756	No alias	tRNA (1-methyladenosine) methyltransferase catalytic...	0.13	OF
EGR49545	No alias	tRNA (1-methyladenosine) methyltransferase catalytic...	0.18	OF
ESU12000	No alias	tRNA (1-methyladenosine) methyltransferase catalytic...	0.07	OF
KHC69644	No alias	tRNA (adenine-N(1)-)-methyltransferase catalytic subunit...	0.18	OF
MGG_04871T0	No alias	tRNA (Adenine-N(1)-)-methyltransferase catalytic subunit...	0.02	OF
SPAC9G1.12.1	No alias	tRNA (m1A) methyltransferase complex catalytic subunit...	0.12	OF

Type	GO Term	Name	Evidence	Source
BP	GO:0001510	RNA methylation	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006396	RNA processing	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006400	tRNA modification	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008033	tRNA processing	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008173	RNA methyltransferase activity	None	Extended
MF	GO:0008175	tRNA methyltransferase activity	None	Extended
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	None	Extended
BP	GO:0009451	RNA modification	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016426	tRNA (adenine) methyltransferase activity	None	Extended
MF	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	IEA	Interproscan
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0030488	tRNA methylation	IEA	Interproscan
CC	GO:0031515	tRNA (m1A) methyltransferase complex	IEA	Interproscan
BP	GO:0032259	methylation	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0034470	ncRNA processing	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
CC	GO:0034708	methyltransferase complex	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043414	macromolecule methylation	None	Extended
CC	GO:0043527	tRNA methyltransferase complex	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1990234	transferase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR014816	tRNA_MeTrfase_Gcd14	72	362

External Links

No external refs found!

YJL125C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation