YIR011C

Description : Protein required for localizing proteasomes to the nucleus; involved in cotranslational protein degradation; mediates interaction between nuclear import factor Srp1p and the proteasome; Sts1p and Srp1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation; involved in ubiquitin-mediated protein degradation [Source:SGD;Acc:S000001450]

Gene families : OG_03_0004586 (OF) Phylogenetic Tree(s): OG0004586_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YIR011C
Cluster	HCCA: Cluster_5

Target	Alias	Description	ECC score	Gene Family Method	Actions
ESU16835	No alias	Tethering factor for nuclear proteasome Cut8/Sts1	0.02	OF
MGG_08586T0	No alias	Tethering factor for nuclear proteasome STS1...	0.03	OF

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	None	Extended
BP	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010498	proteasomal protein catabolic process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
BP	GO:0030163	protein catabolic process	None	Extended
BP	GO:0031144	proteasome localization	IEA	Interproscan
BP	GO:0031503	protein-containing complex localization	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
BP	GO:0034613	cellular protein localization	None	Extended
BP	GO:0034629	cellular protein-containing complex localization	None	Extended
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0070727	cellular macromolecule localization	None	Extended
BP	GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901565	organonitrogen compound catabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR013868	Cut8/Sts1_fam	36	274

External Links

No external refs found!

YIR011C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation