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  5. YHR115C

YHR115C


Description : Ubiquitin-protein ligase (E3); controls septin dynamics, spindle position checkpoint (SPOC) with ligase Dma2p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p; ortholog of human RNF8, similar to human Chfr; contains FHA, RING fingers; DMA1 has a paralog, DMA2, that arose from the whole genome duplication [Source:SGD;Acc:S000001157]


Gene families : OG_03_0002020 (OF) Phylogenetic Tree(s): OG0002020_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YHR115C
Cluster HCCA: Cluster_18


Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR000253 FHA_dom 211 273
IPR001841 Znf_RING 326 354
No external refs found!