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Expression profile for YHR115C (YHR115C)

Description : Ubiquitin-protein ligase (E3); controls septin dynamics, spindle position checkpoint (SPOC) with ligase Dma2p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p; ortholog of human RNF8, similar to human Chfr; contains FHA, RING fingers; DMA1 has a paralog, DMA2, that arose from the whole genome duplication [Source:SGD;Acc:S000001157]

Sample enrichment: YPEG,WT (SPM: 0.25, entropy: 3.2, tau: 0.49)
Perturbation specificity: YPEG (SPM: 0.45, entropy: 2.92, tau: 0.42)

All conditions


Perturbation specificity

Note: SPM calculations for this profile are done using the maximum value.