Description : 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes [Source:SGD;Acc:S000001003]

Gene families : OG_03_0000298 (OF) Phylogenetic Tree(s): OG0000298_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YHL011C
Cluster HCCA: Cluster_69

Target Alias Description ECC score Gene Family Method Actions
AFR96555 No alias ribose-phosphate pyrophosphokinase;Phosphoribosyl... 0.07 OF
AFR98791 No alias ribose-phosphate pyrophosphokinase;N-terminal domain of... 0.04 OF
CAG80285 No alias Ribose-phosphate pyrophosphokinase 0.04 OF
CAG82575 No alias Ribose-phosphate pyrophosphokinase, N-terminal domain 0.04 OF
CAK38850 No alias Phosphoribosyl synthetase-associated domain 0.02 OF
CAK44332 No alias N-terminal domain of ribose phosphate pyrophosphokinase 0.08 OF
CBF83270 No alias ribose-phosphate pyrophosphokinase 0.07 OF
CBF85908 No alias phosphoribosyl diphosphate synthase isoform 4 0.06 OF
EAA26722 No alias Ribose-phosphate pyrophosphokinase, N-terminal domain 0.04 OF
EAL92246 No alias ribose-phosphate pyrophosphokinase 0.03 OF
EDN96027 No alias Ribose-phosphate pyrophosphokinase, N-terminal domain 0.06 OF
ESU17930 No alias ribose-phosphate pyrophosphokinase II 0.07 OF
KHC82253 No alias ribose-phosphate pyrophosphokinase 1;Phosphoribosyl... 0.08 OF
MGG_07148T0 No alias Ribose-phosphate pyrophosphokinase 3... 0.02 OF

Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEA Interproscan
MF GO:0004749 ribose phosphate diphosphokinase activity IEA Interproscan
BP GO:0009165 nucleotide biosynthetic process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR029099 Pribosyltran_N 7 123
IPR005946 Rib-P_diPkinase 204 316
No external refs found!