YGR243W


Description : Highly conserved subunit of the mitochondrial pyruvate carrier (MPC); expressed during growth on nonfermentable carbon sources, and heterodimerizes with Mpc1p to form the respiratory isoform of MPC; MPC localizes to the mitochondrial inner membrane and mediates pyruvate uptake; MPC3 paralog, MPC2, heterodimerizes with Mpc1p to form the fermentative MPC isoform; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003475]


Gene families : OG_03_0002111 (OF) Phylogenetic Tree(s): OG0002111_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YGR243W
Cluster HCCA: Cluster_20


Type GO Term Name Evidence Source
CC GO:0005743 mitochondrial inner membrane IEA Interproscan
BP GO:0006850 mitochondrial pyruvate transmembrane transport IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR005336 MPC 10 116
No external refs found!