YGR243W

Description : Highly conserved subunit of the mitochondrial pyruvate carrier (MPC); expressed during growth on nonfermentable carbon sources, and heterodimerizes with Mpc1p to form the respiratory isoform of MPC; MPC localizes to the mitochondrial inner membrane and mediates pyruvate uptake; MPC3 paralog, MPC2, heterodimerizes with Mpc1p to form the fermentative MPC isoform; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003475]

Gene families : OG_03_0002111 (OF) Phylogenetic Tree(s): OG0002111_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YGR243W
Cluster	HCCA: Cluster_20

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005743	mitochondrial inner membrane	IEA	Interproscan
BP	GO:0006810	transport	None	Extended
BP	GO:0006811	ion transport	None	Extended
BP	GO:0006820	anion transport	None	Extended
BP	GO:0006839	mitochondrial transport	None	Extended
BP	GO:0006848	pyruvate transport	None	Extended
BP	GO:0006850	mitochondrial pyruvate transmembrane transport	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0015711	organic anion transport	None	Extended
BP	GO:0015718	monocarboxylic acid transport	None	Extended
BP	GO:0015849	organic acid transport	None	Extended
CC	GO:0016020	membrane	None	Extended
CC	GO:0019866	organelle inner membrane	None	Extended
CC	GO:0031090	organelle membrane	None	Extended
CC	GO:0031966	mitochondrial membrane	None	Extended
BP	GO:0034220	ion transmembrane transport	None	Extended
BP	GO:0046942	carboxylic acid transport	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0098656	anion transmembrane transport	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
BP	GO:1901475	pyruvate transmembrane transport	None	Extended
BP	GO:1903825	organic acid transmembrane transport	None	Extended
BP	GO:1905039	carboxylic acid transmembrane transport	None	Extended
BP	GO:1990542	mitochondrial transmembrane transport	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR005336	MPC	10	116

External Links

No external refs found!

YGR243W

Expression Profile

Co-expression Networks

Functional Annotation