YGR046W

Description : Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase); required for cardiolipin biosynthesis; viability of null mutant is strain-dependent; mRNA is targeted to the bud; mutant displays defect in mitochondrial protein import, likely due to altered membrane lipid composition [Source:SGD;Acc:S000003278]

Gene families : OG_03_0001729 (OF) Phylogenetic Tree(s): OG0001729_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YGR046W
Cluster	HCCA: Cluster_38

Target	Alias	Description	ECC score	Gene Family Method
AOA66422	No alias	Phosphatidate cytidylyltransferase, mitochondrial	0.04	OF
CAG82065	No alias	Phosphatidate cytidylyltransferase, mitochondrial	0.03	OF
CAK44093	No alias	Phosphatidate cytidylyltransferase, mitochondrial	0.02	OF
EAL90742	No alias	conserved hypothetical protein	0.02	OF
ESU10840	No alias	Phosphatidate cytidylyltransferase, mitochondrial	0.01	OF
POW02964	No alias	Phosphatidate cytidylyltransferase, mitochondrial	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004605	phosphatidate cytidylyltransferase activity	IEA	Interproscan
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006644	phospholipid metabolic process	None	Extended
BP	GO:0006650	glycerophospholipid metabolic process	None	Extended
BP	GO:0006655	phosphatidylglycerol biosynthetic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008610	lipid biosynthetic process	None	Extended
BP	GO:0008654	phospholipid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0032048	cardiolipin metabolic process	None	Extended
BP	GO:0032049	cardiolipin biosynthetic process	IEA	Interproscan
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
BP	GO:0045017	glycerolipid biosynthetic process	None	Extended
BP	GO:0046471	phosphatidylglycerol metabolic process	None	Extended
BP	GO:0046474	glycerophospholipid biosynthetic process	None	Extended
BP	GO:0046486	glycerolipid metabolic process	None	Extended
MF	GO:0070567	cytidylyltransferase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR015222	Tam41	341	380
IPR015222	Tam41	114	325

External Links

No external refs found!

YGR046W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation