YGR029W

Description : Flavin-linked sulfhydryl oxidase of the mitochondrial IMS; N-terminus is an intrinsically disordered domain that in the cytosol helps target Erv1p to mitochondria, and in the intermembrane space oxidizes Mia40p as part of a disulfide relay system that promotes intermembrane space retention of imported proteins; functional ortholog of human GFER (ALR); human GFER carrying N-terminal 21 amino acids of Erv1p functionally complements the lethality of the erv1 null mutation [Source:SGD;Acc:S000003261]

Gene families : OG_03_0000465 (OF) Phylogenetic Tree(s): OG0000465_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	HRR: YGR029W
Cluster	HCCA: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method	Actions
EJF59349	No alias	Erv1 / Alr family	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	None	Extended
MF	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	None	Extended
MF	GO:0016972	thiol oxidase activity	IEA	Interproscan
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR017905	ERV/ALR_sulphydryl_oxidase	92	184

External Links

No external refs found!

YGR029W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation