Description : C-3 sterol dehydrogenase; catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; human homolog NSDHL implicated in CK syndrome, and can complement yeast null mutant; molecular target of natural product and antifungal compound FR171456 [Source:SGD;Acc:S000002969]

Gene families : OG_03_0000748 (OF) Phylogenetic Tree(s): OG0000748_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YGL001C
Cluster HCCA: Cluster_17

Target Alias Description ECC score Gene Family Method Actions
AOA66527 No alias 3-beta hydroxysteroid dehydrogenase/isomerase 0.07 OF
CAG82444 No alias 3-beta hydroxysteroid dehydrogenase/isomerase 0.03 OF
EAL93798 No alias C-3 sterol dehydrogenase/C-4 decarboxylase 0.05 OF
EAU86236 No alias C-3 sterol dehydrogenase 0.1 OF
KHC76700 No alias sterol-4alpha-carboxylate 3-dehydrogenase... 0.1 OF

Type GO Term Name Evidence Source
MF GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity IEA Interproscan
BP GO:0006694 steroid biosynthetic process IEA Interproscan
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR002225 3Beta_OHSteriod_DH/Estase 8 279
No external refs found!