YFR036W

Description : Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000001932]

Gene families : OG_03_0051524 (OF) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YFR036W
Cluster	HCCA: Cluster_3

Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	None	Extended
CC	GO:0000152	nuclear ubiquitin ligase complex	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005680	anaphase-promoting complex	IEA	Interproscan
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0007088	regulation of mitotic nuclear division	None	Extended
BP	GO:0007346	regulation of mitotic cell cycle	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010498	proteasomal protein catabolic process	None	Extended
BP	GO:0010564	regulation of cell cycle process	None	Extended
BP	GO:0010965	regulation of mitotic sister chromatid separation	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEA	Interproscan
BP	GO:0030163	protein catabolic process	None	Extended
BP	GO:0031145	anaphase-promoting complex-dependent catabolic process	IEA	Interproscan
CC	GO:0031461	cullin-RING ubiquitin ligase complex	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033043	regulation of organelle organization	None	Extended
BP	GO:0033044	regulation of chromosome organization	None	Extended
BP	GO:0033045	regulation of sister chromatid segregation	None	Extended
BP	GO:0033047	regulation of mitotic sister chromatid segregation	None	Extended
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051128	regulation of cellular component organization	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0051726	regulation of cell cycle	None	Extended
BP	GO:0051783	regulation of nuclear division	None	Extended
BP	GO:0051983	regulation of chromosome segregation	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901565	organonitrogen compound catabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended
BP	GO:1901987	regulation of cell cycle phase transition	None	Extended
BP	GO:1901990	regulation of mitotic cell cycle phase transition	None	Extended
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
BP	GO:1905818	regulation of chromosome separation	None	Extended
CC	GO:1990234	transferase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR018860	APC_suCDC26	1	85

External Links

No external refs found!

YFR036W

Expression Profile

Co-expression Networks

Functional Annotation