YER151C

Description : Ubiquitin-specific protease involved in transport and osmotic response; negatively regulates Ras/PKA signaling; interacts with Bre5p to coregulate anterograde, retrograde transport between ER and Golgi; involved in transcription elongation in response to osmostress through phosphorylation at Ser695 by Hog1p; inhibitor of gene silencing; role in ribophagy; cleaves ubiquitin fusions but not polyubiquitin; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000000953]

Gene families : OG_03_0003916 (OF) Phylogenetic Tree(s): OG0003916_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YER151C
Cluster	HCCA: Cluster_63

Target	Alias	Description	ECC score	Gene Family Method
AFR94176	No alias	ubiquitin carboxyl-terminal hydrolase 10;Ubiquitin...	0.03	OF
AOA66676	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.03	OF
CAK39738	No alias	Ubiquitin carboxyl-terminal hydrolase	0.03	OF
CBF81041	No alias	ubiquitin C-terminal hydrolase, putative	0.05	OF
EAA31344	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.03	OF
EAL88425	No alias	ubiquitin C-terminal hydrolase, putative	0.04	OF
EDO02379	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.02	OF
EGR44394	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.04	OF
ESU16989	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.05	OF
KHC73170	No alias	ubiquitin carboxyl-terminal hydrolase 10;Ubiquitin...	0.06	OF
MGG_05996T0	No alias	Ubiquitin C-terminal hydrolase...	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008234	cysteine-type peptidase activity	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016579	protein deubiquitination	IEA	Interproscan
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019783	ubiquitin-like protein-specific protease activity	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEA	Interproscan
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0070646	protein modification by small protein removal	None	Extended
BP	GO:0070647	protein modification by small protein conjugation or removal	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0101005	ubiquitinyl hydrolase activity	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001394	Peptidase_C19_UCH	461	908

External Links

No external refs found!

YER151C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation