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  5. YER069W

YER069W


Description : Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase; N-acetyl-L-glutamate kinase (NAGK) catalyzes the 2nd and N-acetyl-gamma-glutamyl-phosphate reductase (NAGSA), the 3rd step in arginine biosynthesis; synthesized as a precursor which is processed in the mitochondrion to yield mature NAGK and NAGSA; enzymes form a metabolon complex with Arg2p; NAGK C-terminal domain stabilizes the enzymes, slows catalysis and is involved in feed-back inhibition by arginine [Source:SGD;Acc:S000000871]


Gene families : OG_03_0001204 (OF) Phylogenetic Tree(s): OG0001204_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YER069W
Cluster HCCA: Cluster_7

Target Alias Description ECC score Gene Family Method Actions
AFR96071 No alias N-acetyl-gamma-glutamyl-phosphate reductase,... 0.03 OF
AOA67591 No alias Vertebrate-like NAGS Gcn5-related N-acetyltransferase... 0.13 OF
CAG83278 No alias Aspartate/glutamate/uridylate kinase 0.04 OF
CAK46382 No alias NAT, N-acetyltransferase, of N-acetylglutamate synthase 0.08 OF
EAL85747 No alias acetylglutamate kinase, putative 0.05 OF
EAU86745 No alias Arg-6 protein 0.04 OF
EGR52523 No alias Vertebrate-like NAGS Gcn5-related N-acetyltransferase... 0.04 OF
EGR53022 No alias Semialdehyde dehydrogenase, NAD-binding 0.14 OF
EJF61495 No alias Amino acid kinase family 0.06 OF
ESA44319 No alias Vertebrate-like NAGS Gcn5-related N-acetyltransferase... 0.14 OF
ESA44320 No alias Vertebrate-like NAGS Gcn5-related N-acetyltransferase... 0.14 OF
ESU10907 No alias N-acetyl-gamma-glutamyl-phosphate reductase 0.05 OF
KHC83677 No alias protein ARG5,6, mitochondrial;Amino acid kinase... 0.07 OF
MGG_02690T0 No alias Arg-6 protein [Source:UniProtKB/TrEMBL;Acc:G5EH72] 0.06 OF
SPAC4G9.09c.1 No alias N-acetyl-gamma-glutamyl-phosphate... 0.06 OF

Type GO Term Name Evidence Source
BP GO:0008652 cellular amino acid biosynthetic process IEA Interproscan
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA Interproscan
MF GO:0046983 protein dimerization activity IEA Interproscan
MF GO:0051287 NAD binding IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR001048 Asp/Glu/Uridylate_kinase 100 316
IPR000534 Semialdehyde_DH_NAD-bd 542 666
IPR006855 Vertebrate-like_GNAT_dom 333 499
IPR012280 Semialdhyde_DH_dimer_dom 696 833
No external refs found!