Description : Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants; protein abundance increases in response to DNA replication stress; TSA2 has a paralog, TSA1, that arose from the whole genome duplication [Source:SGD;Acc:S000002861]
Gene families : OG_03_0005492 (OF) Phylogenetic Tree(s): OG0005492_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDR453C | |
Cluster | HCCA: Cluster_19 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96707 | No alias | peroxiredoxin (alkyl hydroperoxide reductase subunit C),... | 0.02 | OF | |
AGV14565 | No alias | peroxiredoxin (alkyl hydroperoxide reductase subunit C),... | 0.03 | OF | |
AOA66960 | No alias | Peroxiredoxin, C-terminal | 0.1 | OF | |
CAG83166 | No alias | Alkyl hydroperoxide reductase subunit C/ Thiol specific... | 0.04 | OF | |
EAU83474 | No alias | Cys 2 peroxiredoxin | 0.03 | OF | |
ESU10085 | No alias | peroxiredoxin 1 | 0.03 | OF | |
KHC79175 | No alias | peroxiredoxin TSA1;AhpC/TSA family;C-terminal domain of... | 0.07 | OF | |
SPCC576.03c.1 | No alias | thioredoxin peroxidase Tpx1 [Source:PomBase;Acc:SPCC576.03c] | 0.06 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0016209 | antioxidant activity | IEA | Interproscan |
MF | GO:0016491 | oxidoreductase activity | IEA | Interproscan |
MF | GO:0051920 | peroxiredoxin activity | IEA | Interproscan |
BP | GO:0055114 | oxidation-reduction process | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |