Description : Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants; protein abundance increases in response to DNA replication stress; TSA2 has a paralog, TSA1, that arose from the whole genome duplication [Source:SGD;Acc:S000002861]

Gene families : OG_03_0005492 (OF) Phylogenetic Tree(s): OG0005492_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YDR453C
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AFR96707 No alias peroxiredoxin (alkyl hydroperoxide reductase subunit C),... 0.02 OF
AGV14565 No alias peroxiredoxin (alkyl hydroperoxide reductase subunit C),... 0.03 OF
AOA66960 No alias Peroxiredoxin, C-terminal 0.1 OF
CAG83166 No alias Alkyl hydroperoxide reductase subunit C/ Thiol specific... 0.04 OF
EAU83474 No alias Cys 2 peroxiredoxin 0.03 OF
ESU10085 No alias peroxiredoxin 1 0.03 OF
KHC79175 No alias peroxiredoxin TSA1;AhpC/TSA family;C-terminal domain of... 0.07 OF
SPCC576.03c.1 No alias thioredoxin peroxidase Tpx1 [Source:PomBase;Acc:SPCC576.03c] 0.06 OF

Type GO Term Name Evidence Source
MF GO:0016209 antioxidant activity IEA Interproscan
MF GO:0016491 oxidoreductase activity IEA Interproscan
MF GO:0051920 peroxiredoxin activity IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR019479 Peroxiredoxin_C 159 192
IPR000866 AhpC/TSA 5 137
No external refs found!