YDR410C

Description : Farnesyl cysteine-carboxyl methyltransferase; mediates the carboxyl methylation step during C-terminal CAAX motif processing of a-factor and RAS proteins in the endoplasmic reticulum, localizes to the ER membrane [Source:SGD;Acc:S000002818]

Gene families : OG_03_0001506 (OF) Phylogenetic Tree(s): OG0001506_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR410C
Cluster	HCCA: Cluster_57

Target	Alias	Description	ECC score	Gene Family Method
EAU84877	No alias	prenyl cysteine carboxyl methyltransferase Ste14	0.04	OF
EJF61178	No alias	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	0.03	OF
ESU12815	No alias	Isoprenylcysteine carboxyl methyltransferase	0.03	OF
SPAC10F6.12c.1	No alias	protein-S isoprenylcysteine O-methyltransferase Mam4...	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003880	protein C-terminal carboxyl O-methyltransferase activity	None	Extended
MF	GO:0004671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006479	protein methylation	None	Extended
BP	GO:0006481	C-terminal protein methylation	IEA	Interproscan
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008171	O-methyltransferase activity	None	Extended
BP	GO:0008213	protein alkylation	None	Extended
MF	GO:0008276	protein methyltransferase activity	None	Extended
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0010340	carboxyl-O-methyltransferase activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	Interproscan
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0018410	C-terminal protein amino acid modification	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
BP	GO:0032259	methylation	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043414	macromolecule methylation	None	Extended
BP	GO:0043687	post-translational protein modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
MF	GO:0051998	protein carboxyl O-methyltransferase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR007269	ICMT_MeTrfase	127	219

External Links

No external refs found!

YDR410C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation