Description : Dimeric hypoxanthine-guanine phosphoribosyltransferase; catalyzes the transfer of the phosphoribosyl portion of 5-phosphoribosyl-alpha-1-pyrophosphate to a purine base (either guanine or hypoxanthine) to form pyrophosphate and a purine nucleotide (either guanosine monophosphate or inosine monophosphate); mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome [Source:SGD;Acc:S000002807]

Gene families : OG_03_0001699 (OF) Phylogenetic Tree(s): OG0001699_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YDR399W
Cluster HCCA: Cluster_7

Target Alias Description ECC score Gene Family Method Actions
EAL84603 No alias xanthine-guanine phosphoribosyl transferase Xpt1, putative 0.02 OF
EDO02173 No alias Phosphoribosyltransferase domain 0.02 OF
ESU15097 No alias hypoxanthine guanine phosphoribosyltransferase 0.04 OF
MGG_10052T0 No alias Hypoxanthine guanine phosphoribosyltransferase... 0.02 OF

Type GO Term Name Evidence Source
BP GO:0009116 nucleoside metabolic process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000836 PRibTrfase_dom 19 135
No external refs found!