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  5. YDR363W-A

YDR363W-A


Description : 19S proteasome regulatory particle lid subcomplex component; role in Ub-dependent proteolysis and proteasome stability; involved in TREX-2 mediated mRNA export, and in the prevention of transcription-associated genome instability; ubiquitinated by Nedd4-like E3-ligase, Rsp5p; human ortholog DSS1, a BRCA1 binding protein implicated in cancer, complements the yeast null; drives trinucleotide repeat expansion; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000007235]


Gene families : OG_03_0003136 (OF) Phylogenetic Tree(s): OG0003136_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YDR363W-A
Cluster HCCA: Cluster_58

Target Alias Description ECC score Gene Family Method Actions
AFR98640 No alias 26S proteasome complex subunit DSS1;DSS1/SEM1 family 0.04 OF
CAG82461 No alias DSS1/SEM1 0.02 OF
CBF87863 No alias 26 proteasome complex subunit Sem1, putative 0.02 OF

Type GO Term Name Evidence Source
BP GO:0006406 mRNA export from nucleus IEA Interproscan
CC GO:0008541 proteasome regulatory particle, lid subcomplex IEA Interproscan
BP GO:0043248 proteasome assembly IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR007834 DSS1_SEM1 22 82
No external refs found!