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YDR353W


Description : Cytoplasmic thioredoxin reductase; key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress; protein abundance increases in response to DNA replication stress; TRR1 has a paralog, TRR2, that arose from the whole genome duplication [Source:SGD;Acc:S000002761]


Gene families : OG_03_0001496 (OF) Phylogenetic Tree(s): OG0001496_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDR353W
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AOA67322 No alias FAD/NAD(P)-binding domain 0.22 OF
CAG81554 No alias FAD/NAD(P)-binding domain 0.05 OF
CAK43946 No alias Pyridine nucleotide-disulphide oxidoreductase 0.11 OF
CBF75841 No alias Thioredoxin reductase 0.04 OF
EAA36019 No alias FAD/NAD(P)-binding domain 0.03 OF
EAL89494 No alias thioredoxin reductase Trr1/Trr2, putative 0.06 OF
ESU06113 No alias thioredoxin reductase 0.05 OF
KHC75171 No alias thioredoxin reductase;Pyridine nucleotide-disulphide... 0.14 OF
SPBC3F6.03.1 No alias thioredoxin reductase Trr1 [Source:PomBase;Acc:SPBC3F6.03] 0.18 OF

Type GO Term Name Evidence Source
MF GO:0016491 oxidoreductase activity IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR023753 FAD/NAD-binding_dom 5 303
No external refs found!