Description : Catalytic epsilon subunit of the translation initiation factor eIF2B; eIF2B is the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000002619]
Gene families : OG_03_0003724 (OF) Phylogenetic Tree(s): OG0003724_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YDR211W | |
Cluster | HCCA: Cluster_13 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR92658 | No alias | translation initiation factor eIF-2B subunit... | 0.02 | OF | |
AOA69198 | No alias | Nucleotidyl transferase domain | 0.02 | OF | |
CAG83194 | No alias | Nucleotidyl transferase domain | 0.16 | OF | |
CAK48014 | No alias | Bacterial transferase hexapeptide (six repeats) | 0.04 | OF | |
CBF75604 | No alias | translation initiation factor eif-2b epsilon subunit, putative | 0.02 | OF | |
EAA30360 | No alias | W2 domain | 0.04 | OF | |
EAL89093 | No alias | translation initiation factor eif-2b epsilon subunit, putative | 0.06 | OF | |
EAU88454 | No alias | translation initiation factor eif-2b | 0.05 | OF | |
EGR48892 | No alias | Hexapeptide repeat | 0.02 | OF | |
ESU12443 | No alias | Hexapeptide repeat | 0.03 | OF | |
KHC83609 | No alias | translation initiation factor eIF-2B subunit... | 0.05 | OF | |
MGG_03517T0 | No alias | Putative uncharacterized protein... | 0.06 | OF | |
POW13953 | No alias | Hexapeptide repeat;W2 domain | 0.03 | OF | |
SPAC8C9.15c.1 | No alias | translation initiation factor eIF2B epsilon subunit... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | Interproscan |
BP | GO:0009058 | biosynthetic process | IEA | Interproscan |
MF | GO:0016779 | nucleotidyltransferase activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |