YDR211W


Description : Catalytic epsilon subunit of the translation initiation factor eIF2B; eIF2B is the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000002619]


Gene families : OG_03_0003724 (OF) Phylogenetic Tree(s): OG0003724_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDR211W
Cluster HCCA: Cluster_13

Target Alias Description ECC score Gene Family Method Actions
AFR92658 No alias translation initiation factor eIF-2B subunit... 0.02 OF
AOA69198 No alias Nucleotidyl transferase domain 0.02 OF
CAG83194 No alias Nucleotidyl transferase domain 0.16 OF
CAK48014 No alias Bacterial transferase hexapeptide (six repeats) 0.04 OF
CBF75604 No alias translation initiation factor eif-2b epsilon subunit, putative 0.02 OF
EAA30360 No alias W2 domain 0.04 OF
EAL89093 No alias translation initiation factor eif-2b epsilon subunit, putative 0.06 OF
EAU88454 No alias translation initiation factor eif-2b 0.05 OF
EGR48892 No alias Hexapeptide repeat 0.02 OF
ESU12443 No alias Hexapeptide repeat 0.03 OF
KHC83609 No alias translation initiation factor eIF-2B subunit... 0.05 OF
MGG_03517T0 No alias Putative uncharacterized protein... 0.06 OF
POW13953 No alias Hexapeptide repeat;W2 domain 0.03 OF
SPAC8C9.15c.1 No alias translation initiation factor eIF2B epsilon subunit... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
BP GO:0009058 biosynthetic process IEA Interproscan
MF GO:0016779 nucleotidyltransferase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR005835 NTP_transferase_dom 30 156
IPR001451 Hexapep 331 361
IPR001451 Hexapep 382 420
IPR003307 W2_domain 634 710
No external refs found!