YDR211W

Description : Catalytic epsilon subunit of the translation initiation factor eIF2B; eIF2B is the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; forms cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000002619]

Gene families : OG_03_0003724 (OF) Phylogenetic Tree(s): OG0003724_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR211W
Cluster	HCCA: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method
AFR92658	No alias	translation initiation factor eIF-2B subunit...	0.02	OF
AOA69198	No alias	Nucleotidyl transferase domain	0.02	OF
CAG83194	No alias	Nucleotidyl transferase domain	0.16	OF
CAK48014	No alias	Bacterial transferase hexapeptide (six repeats)	0.04	OF
CBF75604	No alias	translation initiation factor eif-2b epsilon subunit, putative	0.02	OF
EAA30360	No alias	W2 domain	0.04	OF
EAL89093	No alias	translation initiation factor eif-2b epsilon subunit, putative	0.06	OF
EAU88454	No alias	translation initiation factor eif-2b	0.05	OF
EGR48892	No alias	Hexapeptide repeat	0.02	OF
ESU12443	No alias	Hexapeptide repeat	0.03	OF
KHC83609	No alias	translation initiation factor eIF-2B subunit...	0.05	OF
MGG_03517T0	No alias	Putative uncharacterized protein...	0.06	OF
POW13953	No alias	Hexapeptide repeat;W2 domain	0.03	OF
SPAC8C9.15c.1	No alias	translation initiation factor eIF2B epsilon subunit...	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	IEA	Interproscan
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	IEA	Interproscan

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR005835	NTP_transferase_dom	30	156
IPR001451	Hexapep	331	361
IPR001451	Hexapep	382	420
IPR003307	W2_domain	634	710

External Links

No external refs found!

YDR211W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation