YDR170C

Description : Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors; involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles [Source:SGD;Acc:S000002577]

Gene families : OG_03_0002075 (OF) Phylogenetic Tree(s): OG0002075_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR170C
Cluster	HCCA: Cluster_8

Target	Alias	Description	ECC score	Gene Family Method
AFR95020	No alias	guanine nucleotide exchange protein for ADP-robosylation...	0.12	OF
AOA66650	No alias	Guanine nucleotide exchange factor, N-terminal	0.23	OF
CAG81392	No alias	Mon2, dimerisation and cyclophilin-binding domain	0.13	OF
CAK39310	No alias	Guanine nucleotide exchange factor in Golgi transport N-terminal	0.13	OF
CBF71296	No alias	guanyl-nucleotide exchange factor	0.16	OF
EAA33549	No alias	Sec7, C-terminal	0.15	OF
EAL86902	No alias	guanyl-nucleotide exchange factor (Sec7), putative	0.22	OF
EAU84758	No alias	Sec7p	0.13	OF
EDN99213	No alias	Guanine nucleotide exchange factor, N-terminal	0.12	OF
EED81455	No alias	Mon2, dimerisation and cyclophilin-binding domain	0.05	OF
EGR52763	No alias	Guanine nucleotide exchange factor, N-terminal	0.19	OF
ESU08962	No alias	Sec7 domain	0.11	OF
KHC79025	No alias	hypothetical protein;Domain of unknown function...	0.34	OF
MGG_14173T0	No alias	Transporter SEC7 [Source:UniProtKB/TrEMBL;Acc:G4NIC8]	0.11	OF
SPAC30.01c.1	No alias	Sec7 domain protein, ARF GEF Sec72...	0.18	OF
SPAC4D7.01c.1	No alias	Sec7 domain protein, ARF GEF (predicted)...	0.17	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005085	guanyl-nucleotide exchange factor activity	None	Extended
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009966	regulation of signal transduction	None	Extended
BP	GO:0010646	regulation of cell communication	None	Extended
MF	GO:0019899	enzyme binding	None	Extended
BP	GO:0023051	regulation of signaling	None	Extended
BP	GO:0032012	regulation of ARF protein signal transduction	IEA	Interproscan
BP	GO:0046578	regulation of Ras protein signal transduction	None	Extended
BP	GO:0048583	regulation of response to stimulus	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
MF	GO:0051020	GTPase binding	None	Extended
BP	GO:0051056	regulation of small GTPase mediated signal transduction	None	Extended
BP	GO:0065007	biological regulation	None	Extended
MF	GO:0098772	molecular function regulator	None	Extended
BP	GO:1902531	regulation of intracellular signal transduction	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR032691	Sec7_N	497	663
IPR000904	Sec7_dom	827	1010
IPR015403	Sec7_C	1369	1446
IPR032629	DCB_dom	227	426

External Links

No external refs found!

YDR170C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation