Description : Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A; N-terminally propionylated in vivo; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002562]
Gene families : OG_03_0000094 (OF) Phylogenetic Tree(s): OG0000094_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YDR155C | |
| Cluster | HCCA: Cluster_8 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR93130 | No alias | peptidyl-prolyl cis-trans isomerase;Cyclophilin type... | 0.04 | OF | |
| AOA66347 | No alias | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | 0.02 | OF | |
| CAG81971 | No alias | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | 0.03 | OF | |
| CAK48212 | No alias | cyclophilin-like peptidyl prolyl cis-trans isomerase... | 0.02 | OF | |
| EAL87466 | No alias | peptidyl-prolyl cis-trans isomerase | 0.03 | OF | |
| EDO03529 | No alias | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | 0.01 | OF | |
| EGR48175 | No alias | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | 0.03 | OF | |
| ESA44269 | No alias | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | 0.01 | OF | |
| KHC71922 | No alias | peptidyl-prolyl cis-trans isomerase;Cyclophilin type... | 0.06 | OF | |
| MGG_10447T0 | No alias | Peptidyl-prolyl cis-trans isomerase... | 0.02 | OF | |
| MGG_11257T0 | No alias | Peptidyl-prolyl cis-trans isomerase H... | 0.02 | OF | |
| POW06012 | No alias | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | 0.02 | OF | |
| SPBC28F2.03.1 | No alias | cyclophilin family peptidyl-prolyl cis-trans isomerase... | 0.03 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| BP | GO:0000413 | protein peptidyl-prolyl isomerization | IEA | Interproscan |
| MF | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR002130 | Cyclophilin-type_PPIase_dom | 6 | 157 |
| No external refs found! |