YDR001C

Description : Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; phosphorylated and activated by Cdc28p at the G1/S phase transition to coordinately regulate carbohydrate metabolism and the cell cycle; inhibited by Dcs1p; NTH1 has a paralog, NTH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002408]

Gene families : OG_03_0000709 (OF) Phylogenetic Tree(s): OG0000709_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDR001C
Cluster	HCCA: Cluster_45

Target	Alias	Description	ECC score	Gene Family Method
AFR93292	No alias	alpha,alpha-trehalase;Trehalase;Neutral trehalase Ca2+...	0.02	OF
AOA70049	No alias	Glycoside hydrolase, family 37	0.05	OF
CAK43979	No alias	Neutral trehalase Ca2+ binding domain	0.04	OF
CBF81508	No alias	Neutral trehalase	0.02	OF
EED78320	No alias	Glycoside hydrolase, family 37	0.04	OF
EED84284	No alias	Glycoside hydrolase, family 37	0.03	OF
KHC71038	No alias	neutral trehalase;Neutral trehalase Ca2+ binding domain;Trehalase	0.02	OF
MGG_09471T0	No alias	Neutral trehalase [Source:UniProtKB/Swiss-Prot;Acc:O42622]	0.03	OF
POW02420	No alias	Glycoside hydrolase, family 37	0.02	OF
SPBC660.07.1	No alias	alpha,alpha-trehalase Ntp1 [Source:PomBase;Acc:SPBC660.07]	0.08	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	None	Extended
MF	GO:0004555	alpha,alpha-trehalase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005509	calcium ion binding	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	Interproscan
BP	GO:0005975	carbohydrate metabolic process	None	Extended
BP	GO:0005984	disaccharide metabolic process	None	Extended
BP	GO:0005991	trehalose metabolic process	IEA	Interproscan
BP	GO:0005993	trehalose catabolic process	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009311	oligosaccharide metabolic process	None	Extended
BP	GO:0009313	oligosaccharide catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0015927	trehalase activity	None	Extended
BP	GO:0016052	carbohydrate catabolic process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044262	cellular carbohydrate metabolic process	None	Extended
BP	GO:0044275	cellular carbohydrate catabolic process	None	Extended
BP	GO:0046352	disaccharide catabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR011120	Trehalase_Ca-bd	106	135
IPR001661	Glyco_hydro_37	163	721

External Links

No external refs found!

YDR001C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation