Description : Subunit of a replication-pausing checkpoint complex; Tof1p-Mrc1p-Csm3p acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005217]
Sample enrichment: gal, 2h + hu 200 mm,WT (SPM: 0.31, entropy: 3.66, tau: 0.62)