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Expression profile for YPR140W (YPR140W)

Description : Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin (TAZ) cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia; a specific splice variant of human TAZ can complement yeast null mutant [Source:SGD;Acc:S000006344]

Sample enrichment: ypsorbitol (2.02%),YPD,WT (SPM: 0.32, entropy: 3.57, tau: 0.62)
Perturbation specificity: YPD, sorbitol (SPM: 0.51, entropy: 3.02, tau: 0.53)