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YPR140W


Description : Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin (TAZ) cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia; a specific splice variant of human TAZ can complement yeast null mutant [Source:SGD;Acc:S000006344]


Gene families : OG_03_0002746 (OF) Phylogenetic Tree(s): OG0002746_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YPR140W
Cluster HCCA: Cluster_53


Type GO Term Name Evidence Source
MF GO:0016746 transferase activity, transferring acyl groups IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR002123 Plipid/glycerol_acylTrfase 65 226
No external refs found!