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Expression profile for YMR089C (YMR089C)

Description : Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; overexpression of human AFG3L2 complements respiratory defect of yeast afg3 yta12 double null mutation, but overexpression of disease-associated AFG3L2 variants does not; expression of both human SPG7 (paraplegin) and AFG3L2 complements yeast yta12 afg3 double mutation [Source:SGD;Acc:S000004695]

Sample enrichment: synthetic complete med,20C,WT (SPM: 0.3, entropy: 3.66, tau: 0.6)
Perturbation specificity: YPD (SPM: 0.47, entropy: 3.08, tau: 0.5)

All conditions


Perturbation specificity

Note: SPM calculations for this profile are done using the maximum value.