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Expression profile for YLR143W (YLR143W)

Description : Diphthamide synthetase; catalyzes the last amidation step of diphthamide biosynthesis using ammonium and ATP; evolutionarily conserved in eukaryotes; dph6 mutants exhibit diphthine accumulation and resistance to sordarin, which is indicative of defects in diphthamide formation on EF2; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; DPH6/YLR143W is not an essential gene [Source:SGD;Acc:S000004133]

Sample enrichment: gal, 4h + hu 200 mm,WT (SPM: 0.25, entropy: 3.86, tau: 0.49)
Perturbation specificity: Gal (SPM: 0.49, entropy: 3.08, tau: 0.5)