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  5. YLR143W

YLR143W


Description : Diphthamide synthetase; catalyzes the last amidation step of diphthamide biosynthesis using ammonium and ATP; evolutionarily conserved in eukaryotes; dph6 mutants exhibit diphthine accumulation and resistance to sordarin, which is indicative of defects in diphthamide formation on EF2; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; DPH6/YLR143W is not an essential gene [Source:SGD;Acc:S000004133]


Gene families : OG_03_0002473 (OF) Phylogenetic Tree(s): OG0002473_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YLR143W
Cluster HCCA: Cluster_63

Target Alias Description ECC score Gene Family Method Actions
KHC81437 No alias TIGR00289 family protein;Endoribonuclease... 0.05 OF
POW07953 No alias Diphthamide synthase domain;YjgF/YER057c/UK114 family 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR002761 Diphthami_syn_dom 1 231
IPR006175 YjgF/YER057c/UK114 332 416
No external refs found!