YLR143W


Description : Diphthamide synthetase; catalyzes the last amidation step of diphthamide biosynthesis using ammonium and ATP; evolutionarily conserved in eukaryotes; dph6 mutants exhibit diphthine accumulation and resistance to sordarin, which is indicative of defects in diphthamide formation on EF2; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; DPH6/YLR143W is not an essential gene [Source:SGD;Acc:S000004133]


Gene families : OG_03_0002473 (OF) Phylogenetic Tree(s): OG0002473_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLR143W
Cluster HCCA: Cluster_63

Target Alias Description ECC score Gene Family Method Actions
KHC81437 No alias TIGR00289 family protein;Endoribonuclease... 0.05 OF
POW07953 No alias Diphthamide synthase domain;YjgF/YER057c/UK114 family 0.03 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR002761 Diphthami_syn_dom 1 231
IPR006175 YjgF/YER057c/UK114 332 416
No external refs found!