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Expression profile for YER125W (YER125W)

Description : NEDD4 family E3 ubiquitin ligase; regulates processes including: MVB sorting, the heat shock response, transcription, endocytosis and ribosome stability; ubiquitinates Sec23p, Sna3p, Ste4p, Nfi1p, Rpo21p and Sem1p; autoubiquitinates; deubiquitinated by Ubp2p; regulated by SUMO ligase Siz1p, in turn regulates Siz1p SUMO ligase activity; required for efficient Golgi-to-ER trafficking in COPI mutants; mutant tolerates aneuploidy; human homolog implicated in Liddle syndrome [Source:SGD;Acc:S000000927]

Sample enrichment: YP + 3% glycerol,WT (SPM: 0.27, entropy: 3.81, tau: 0.54)
Perturbation specificity: YPD (SPM: 0.45, entropy: 3.02, tau: 0.43)

All conditions


Perturbation specificity

Note: SPM calculations for this profile are done using the maximum value.