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Expression profile for YML130C (YML130C)

Description : Thiol oxidase required for oxidative protein folding in the ER; essential for maintaining ER redox balance; feedback regulated via reduction and oxidation of regulatory bonds; reduced Pdi1p activates Ero1p by direct reduction of Ero1p regulatory bonds; depletion of thiol substrates and accumulation of oxidized Pdi1p results in inactivation of Ero1p by both Pdi1p-mediated oxidation and autonomous oxidation of Ero1p regulatory bonds; ero1-1 mutation complemented by human ERO1L [Source:SGD;Acc:S000004599]

Sample enrichment: 200 mm hu,WT (SPM: 0.38, entropy: 3.61, tau: 0.72)
Perturbation specificity: YPD, tunicamycin (SPM: 0.72, entropy: 2.75, tau: 0.74)

All conditions


Perturbation specificity

Note: SPM calculations for this profile are done using the maximum value.