Expression profile for YNL088W (YNL088W)

Description : Topoisomerase II; relieves torsional strain in DNA by cleaving and re-sealing phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis; required for replication slow zone (RSZ) breakage following Mec1p inactivation; human homolog TOP2A implicated in cancers, and can complement yeast null mutant [Source:SGD;Acc:S000005032]

Sample enrichment: gal, 4h + hu 200 mm,WT (SPM: 0.38, entropy: 3.33, tau: 0.76)
Perturbation specificity: Gal (SPM: 0.83, entropy: 2.52, tau: 0.83)

All conditions


Perturbation specificity

Note: SPM calculations for this profile are done using the maximum value.