Description : Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication [Source:SGD;Acc:S000003030]
Sample enrichment: gal, 2h + hu 200 mm,WT (SPM: 0.48, entropy: 3.26, tau: 0.8)