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  5. YGL062W

YGL062W


Description : Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication [Source:SGD;Acc:S000003030]


Gene families : OG_03_0000155 (OF) Phylogenetic Tree(s): OG0000155_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YGL062W
Cluster HCCA: Cluster_7

Target Alias Description ECC score Gene Family Method Actions
EGR46537 No alias Biotin carboxylase-like, N-terminal domain 0.03 OF
ESU14625 No alias Biotin carboxylase, C-terminal 0.03 OF
KHC76480 No alias pyruvate carboxylase;Conserved carboxylase... 0.07 OF
KHC77660 No alias pyruvate carboxylase;Conserved carboxylase... 0.07 OF
SPBC17G9.11c.1 No alias pyruvate carboxylase Pyr1 [Source:PomBase;Acc:SPBC17G9.11c] 0.13 OF

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR003379 Carboxylase_cons_dom 851 1051
IPR000089 Biotin_lipoyl 1103 1167
IPR000891 PYR_CT 559 827
IPR005479 CbamoylP_synth_lsu-like_ATP-bd 135 343
IPR005481 BC-like_N 20 130
IPR005482 Biotin_COase_C 359 466
No external refs found!