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Expression profile for YDR217C (YDR217C)

Description : DNA damage-dependent checkpoint protein; required for cell-cycle arrest in G1/S, intra-S, and G2/M, plays a role in postreplication repair (PRR) pathway; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; multiple cyclin dependent kinase consensus sites and the C-terminal BRCT domain contribute to DNA damage checkpoint activation; Rad9p Chk1 Activating Domain (CAD) is phosphorylated at multiple sites by Cdc28p/Clb2p [Source:SGD;Acc:S000002625]

Sample enrichment: gal, 4h + hu 200 mm,WT (SPM: 0.31, entropy: 3.83, tau: 0.65)
Perturbation specificity: Gal (SPM: 0.65, entropy: 3.02, tau: 0.7)