1. Home
2. Expression Profile
3. YDR143C

Expression profile for YDR143C (YDR143C)

Description : Ubiquitin-protein ligase; involved in proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition; prefers a window of exposed hydrophobicity that causes a particular level of protein insolubility, suggesting that San1p evolved to target highly aggregation-prone proteins [Source:SGD;Acc:S000002550]

Sample enrichment: YPEG,WT (SPM: 0.29, entropy: 3.17, tau: 0.55)
Perturbation specificity: YPEG (SPM: 0.51, entropy: 2.63, tau: 0.51)