GO:0006099: tricarboxylic acid cycle (Biological process)

"A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle." [ISBN:0198506732]


There are 19 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_31 Saccharomyces cerevisiae 2.08 % 0.007273 0.01193
Cluster_86 Aspergillus fumigatus 1.61 % 0.006443 0.045545
Cluster_62 Aspergillus niger 1.54 % 0.004662 0.039715
Cluster_84 Candida albicans 50.0 % 0.000626 0.00438
Cluster_136 Coprinopsis cinerea 1.56 % 0.004792 0.039875
Cluster_19 Fusarium graminearum 0.52 % 0.014572 0.03976
Cluster_10 Postia placenta 0.96 % 0.01145 0.029295
Cluster_15 Puccinia striiformis 0.56 % 0.011796 0.024601
Sequences (19) (download table)

InterPro Domains

GO Terms

Family Terms