YDL188C


Description : Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; dephosphorylates Tel1p/Mec1p-phosphorylated Cdc13p to promote telomerase release from telomeres at G2/M; PPH22 has a paralog, PPH21, that arose from the whole genome duplication [Source:SGD;Acc:S000002347]


Gene families : OG_03_0000082 (OF) Phylogenetic Tree(s): OG0000082_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDL188C
Cluster HCCA: Cluster_46

Target Alias Description ECC score Gene Family Method Actions
CAK48275 No alias Calcineurin-like phosphoesterase 0.06 OF
EAA32582 No alias Calcineurin-like phosphoesterase domain, ApaH type 0.02 OF
EDN98615 No alias Calcineurin-like phosphoesterase domain, ApaH type 0.02 OF
EGR51741 No alias Calcineurin-like phosphoesterase domain, ApaH type 0.04 OF
ESU16445 No alias serine/threonine-protein phosphatase PP2A catalytic subunit 0.02 OF

Type GO Term Name Evidence Source
MF GO:0016787 hydrolase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR004843 Calcineurin-like_PHP_ApaH 119 310
No external refs found!