Description : Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; forms nuclear foci upon DNA replication stress; PPH21 has a paralog, PPH22, that arose from the whole genome duplication [Source:SGD;Acc:S000002292]
Gene families : OG_03_0000082 (OF) Phylogenetic Tree(s): OG0000082_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YDL134C | |
| Cluster | HCCA: Cluster_46 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AFR92541 | No alias | serine/threonine-protein phosphatase PP-X isozyme... | 0.03 | OF | |
| CAK44083 | No alias | Calcineurin-like phosphoesterase | 0.02 | OF | |
| EAA32582 | No alias | Calcineurin-like phosphoesterase domain, ApaH type | 0.05 | OF | |
| EAL91412 | No alias | serine/threonine protein phosphatase, putative | 0.02 | OF | |
| EGR51741 | No alias | Calcineurin-like phosphoesterase domain, ApaH type | 0.02 | OF | |
| ESU16445 | No alias | serine/threonine-protein phosphatase PP2A catalytic subunit | 0.04 | OF | |
| MGG_06099T0 | No alias | Serine/threonine-protein phosphatase PP2A catalytic... | 0.02 | OF | |
| POV94976 | No alias | Calcineurin-like phosphoesterase domain, ApaH type | 0.02 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0016787 | hydrolase activity | IEA | Interproscan |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR004843 | Calcineurin-like_PHP_ApaH | 111 | 302 |
| No external refs found! |