YDL126C

Description : AAA ATPase; subunit of polyUb-selective segregase complex involved in ERAD, INM-associated degradation (INMAD), mitotic spindle disassembly, macroautophagy, PMN, ribosome-associated degradation, ribophagy, homotypic ER membrane fusion, SCF complex disassembly, cell wall integrity during heat stress, and telomerase regulation; mobilizes membrane-anchored transcription factors by regulated Ub/proteasome-dependent processing (RUP); human ortholog VCP complements a cdc48 mutant [Source:SGD;Acc:S000002284]

Gene families : OG_03_0000176 (OF) Phylogenetic Tree(s): OG0000176_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YDL126C
Cluster	HCCA: Cluster_33

Target	Alias	Description	ECC score	Gene Family Method
AFR97364	No alias	transitional endoplasmic reticulum ATPase;Vps4 C...	0.07	OF
AOA69460	No alias	ATPase, AAA-type, core	0.1	OF
CAG78126	No alias	Vps4 oligomerisation, C-terminal	0.04	OF
CAK39004	No alias	Vps4 C terminal oligomerisation domain	0.06	OF
CBF78760	No alias	Cell division control protein 48	0.07	OF
EGR46048	No alias	CDC48, N-terminal subdomain	0.09	OF
ESA43229	No alias	CDC48, domain 2	0.1	OF
ESA43230	No alias	CDC48, domain 2	0.1	OF
ESU11502	No alias	cell division cycle protein 48	0.15	OF
KHC83823	No alias	cell division control protein 48;AAA+ lid domain;"Cell...	0.11	OF
MGG_05193T0	No alias	Cell division control protein 48...	0.05	OF
MGG_13203T0	No alias	ATPase [Source:UniProtKB/TrEMBL;Acc:G4N5K9]	0.03	OF
SPAC1565.08.1	No alias	AAA family ATPase involved in ubiquitin-mediated protein...	0.09	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
MF	GO:0008144	drug binding	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR015415	Vps4_C	751	783
IPR003338	CDC4_N-term_subdom	36	116
IPR004201	Cdc48_dom2	136	198
IPR041569	AAA_lid_3	403	443
IPR041569	AAA_lid_3	682	717
IPR003959	ATPase_AAA_core	524	657
IPR003959	ATPase_AAA_core	251	380

External Links

No external refs found!

YDL126C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation