YDL126C


Description : AAA ATPase; subunit of polyUb-selective segregase complex involved in ERAD, INM-associated degradation (INMAD), mitotic spindle disassembly, macroautophagy, PMN, ribosome-associated degradation, ribophagy, homotypic ER membrane fusion, SCF complex disassembly, cell wall integrity during heat stress, and telomerase regulation; mobilizes membrane-anchored transcription factors by regulated Ub/proteasome-dependent processing (RUP); human ortholog VCP complements a cdc48 mutant [Source:SGD;Acc:S000002284]


Gene families : OG_03_0000176 (OF) Phylogenetic Tree(s): OG0000176_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YDL126C
Cluster HCCA: Cluster_33

Target Alias Description ECC score Gene Family Method Actions
AFR97364 No alias transitional endoplasmic reticulum ATPase;Vps4 C... 0.07 OF
AOA69460 No alias ATPase, AAA-type, core 0.1 OF
CAG78126 No alias Vps4 oligomerisation, C-terminal 0.04 OF
CAK39004 No alias Vps4 C terminal oligomerisation domain 0.06 OF
CBF78760 No alias Cell division control protein 48 0.07 OF
EGR46048 No alias CDC48, N-terminal subdomain 0.09 OF
ESA43229 No alias CDC48, domain 2 0.1 OF
ESA43230 No alias CDC48, domain 2 0.1 OF
ESU11502 No alias cell division cycle protein 48 0.15 OF
KHC83823 No alias cell division control protein 48;AAA+ lid domain;"Cell... 0.11 OF
MGG_05193T0 No alias Cell division control protein 48... 0.05 OF
MGG_13203T0 No alias ATPase [Source:UniProtKB/TrEMBL;Acc:G4N5K9] 0.03 OF
SPAC1565.08.1 No alias AAA family ATPase involved in ubiquitin-mediated protein... 0.09 OF

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR015415 Vps4_C 751 783
IPR003338 CDC4_N-term_subdom 36 116
IPR004201 Cdc48_dom2 136 198
IPR041569 AAA_lid_3 403 443
IPR041569 AAA_lid_3 682 717
IPR003959 ATPase_AAA_core 524 657
IPR003959 ATPase_AAA_core 251 380
No external refs found!